A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

A vial of a plant-derived COVID-19 vaccine candidate, developed by Medicago, is shown in Quebec City on Monday, July 13, 2020 as part of the company’s Phase 1 clinical trials in this handout photo. Medicago says it has received promising early test results for its plant-derived vaccine for COVID-19. THE CANADIAN PRESS/HO, Medicago

Canadian company reports promising early Phase 1 test results of possible COVID-19 vaccine

Quebec City-based company says the side-effects were generally mild to moderate and short in duration

A Canadian biopharmaceutical company says it has received promising early test results for its plant-derived vaccine for COVID-19.

Privately held Medicago says interim results of a Phase 1 clinical trial found that 100 per cent of subjects developed an antibody response after two doses of its COVID-19 vaccine candidate.

“These are very promising results,” said Nathalie Landry, Medicago’s executive vice-president of scientific and medical affairs in a news release.

“We also observed that the antibody levels were higher after vaccination than those observed in convalescent sera from people who recovered from the disease.”

The Quebec City-based company says the side-effects were generally mild to moderate and short in duration.

The Phase 1 clinical trial was a randomized, partially blinded study of 180 healthy people.

Based on the Phase 1 data, Medicago plans to proceed with a Phase 2/3 clinical trial for its COVID-19 vaccine candidate, subject to regulatory approval.

The news comes a day after stock markets worldwide rallied on a report from Pfizer that a potential COVID-19 vaccine it’s developing with German partner BioNTech may be 90 per cent effective, based on early but incomplete test results.

“The positive results of our Phase 1 clinical trial are a step forward in the fight against the COVID-19 pandemic and we are confidently moving forward to our Phase 2/3 trial. We’re pleased that Medicago’s innovative manufacturing technology is helping to diversify the classes of COVID-19 vaccines candidates in development,” said CEO Dr. Bruce Clark.

The federal government has signed a deal with Medicago to secure the rights to buy 76 million doses of its vaccine.

VIDEO: Trudeau says he hopes to see COVID-19 vaccines roll out in Canada in early 2021

Medicago will also receive $173 million in funding from Ottawa for its vaccine research and development and for the construction of its Quebec City manufacturing facility.

Ottawa is also investing $18.2 million in a potential vaccine from British Columbia’s Precision NanoSystems and the National Research Council is to spend $23 million to support other Canadian vaccine initiatives.

Medicago was founded in 1999 and says its team includes over 450 scientific experts and employees in Canada and the United States, with academic affiliations in Europe and South Africa.

The Canadian Press


Like us on Facebook and follow us on Twitter.

Want to support local journalism during the pandemic? Make a donation here.

Coronavirusvaccines

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

Masks are mandatory for passengers on board BC Transit buses and for those waiting at covered bus stops. (BC Transit/Facebook)
Masks now mandatory on BC Transit buses, at covered bus stops

Face shields no longer meet face-covering requirements per updated policy

Rose Ellis, 93, and her Shih Tzu, Zoey, have been clients of ElderDog Victoria since last summer. (Jane Skrypnek/News Staff)
Victoria ElderDog program seeking more seniors, pups to support

Service helps elderly people to care for their canine companions

Mona Strelaeff, a Metchosin resident, is the first non-terminally ill person in Canada to be allowed to use psilocybin assisted therapy. (Provided by Spencer Hawkswell)
Metchosin woman’s trauma treatment could be trendsetting

Experts say this could signal the broadening of who can access psilocybin therapy

Sidney’s Haunted Bookshop is changing owners with longtime owner Odean Long transferring ownership Dec. 1 to William Matthews. (Wolf Depner/News Staff)
Longtime owner of Sidney’s Haunted Bookshop closes chapter with sale

Odean Long and her late husband moved the business to Sidney in 1996

Goldstream Food Bank volunteers at work. Light Up the City will be offering various options for the public to drop off non-perishable food items to support this food bank and others in Greater Victoria. (Black Press Media file photo)
Greater Victoria residents can show their charity through Light Up the City

Drive-thru food bank and toy donation dropoff sites open up this Saturday around region

Mary Cox and Jack Plant dance in their pyjamas and slippers at the morning pyjama dance during the Rhythm Reelers’ 25 Annual Rally in the Valley Square Dance Festival in Chilliwack on June 4, 2011. Sunday, Nov. 29, 2020 is Square Dancing Day. (Jenna Hauck/ Chilliwack Progress file)
Unofficial holidays: Here’s what people are celebrating for the week of Nov. 29 to Dec. 5

Square Dancing Day, Disability Day and International Ninja Day are all coming up this week

Black Press Media and BraveFace have come together to support children facing life-threatening conditions. Net proceeds from these washable, reusable, three-layer masks go to Make-A-Wish Foundation BC & Yukon.
Put on a BraveFace: Help make children’s wishes come true

Black Press Media, BraveFace host mask fundraiser for Make-A-Wish Foundation

A photo from 2017, of Nuchatlaht First Nation members outside court after filing a land title case in B.C. ( Submitted photo/Nuchatlaht First Nation).
Vancouver Island First Nation calls on B.C. to honour UNDRIP in historic title case

Nuchatlaht First Nation says Crown counsel continues to stall the case using the ‘distasteful’ argument that the Nation ‘abandoned’ their land

West Vancouver Island’s Ehattesaht First Nation continues lock down after 9 active cases were reported today after a visitor tested positive last week. (Ehattesaht First Nation/Facebook)
Ehattesaht First Nation’s COVID-19 nightmare: nine active cases, a storm and a power outage

The Vancouver Island First Nation in a lockdown since the first case was reported last week

114 Canadians were appointed Nov. 27 to the Order of Canada. (Governor General of Canada photo)
Indigenous actor, author, elder, leaders appointed to Order of Canada

Outstanding achievement, community dedication and service recognized

The Ahousaht First Nation confirmed its first case of COVID-19 on Nov. 26, 2020. (Westerly file photo)
Ahousaht First Nation on lockdown over COVID-19

“Emotions are high. The anxiety is high. We want our community to pull through.”

Screenshot of Pastor James Butler giving a sermon at Free Grace Baptist Church in Chilliwack on Nov. 22, 2020. The church has decided to continue in-person services despite a public health order banning worship services that was issued on Nov. 19, 2020. (YouTube)
2 Lower Mainland churches continue in-person services despite public health orders

Pastors say faith groups are unfairly targeted and that charter rights protect their decisions

Most Read